GABA antibodies

ImmuSmol provides a complete range of high-quality anti-GABA antibodies designed to deliver reliable and reproducible results in neuroscience research. GABA, or γ-aminobutyric acid, is the brain’s primary inhibitory neurotransmitter, and accurate detection of this molecule is essential for exploring neuronal activity, synaptic regulation, and the mechanisms underlying neurological disorders. To support such studies, ImmuSmol offers three complementary anti-GABA antibodies—chicken polyclonal, mouse monoclonal, and rabbit polyclonal—that have all been extensively validated for immunofluorescence, immunocytochemistry, and immunohistochemistry applications. The chicken polyclonal anti-GABA antibody is particularly useful for multiplex experiments, as its distinct host species enables researchers to combine it with other primary antibodies without cross-reactivity issues. It has been successfully applied to the labeling of primary neurons and brain tissues, ensuring robust and specific detection of GABAergic systems. The mouse monoclonal antibody provides another strong option, offering the high specificity and reproducibility that monoclonal antibodies are known for. This reagent is especially well suited for advanced in vitro models such as neuronal organoids, where consistent performance across experiments is critical. Completing the panel, the rabbit polyclonal anti-GABA antibody (IS1006) is a high-affinity reagent that demonstrates excellent sensitivity with minimal cross-reactivity toward structurally related molecules such as β-alanine or D-alanine. Validated in both cultured cells and tissue samples, across rodent and human models, this antibody has become a reliable choice for researchers aiming to achieve accurate and detailed visualization of GABA distribution. All three antibodies are fully compatible with the STAINperfect™ immunostaining kit, a solution designed to maximize labeling efficiency and reproducibility across different experimental systems. By combining the antibodies with this kit, scientists can achieve clear and consistent GABA imaging in primary neurons, iPSC-derived neurons, brain tissues, and organoid models. This makes the ImmuSmol portfolio a trusted resource for laboratories studying GABAergic signaling, whether the goal is to investigate neurotransmission, characterize neuronal networks, or explore the role of GABA in neurological diseases. With its versatile selection of host species, proven performance in peer-reviewed publications, and compatibility with multiplex staining strategies, ImmuSmol’s collection of anti-GABA antibodies offers a reliable foundation for any project focused on GABA imaging. By supporting accurate immunofluorescence and immunohistochemistry, these antibodies provide scientists with the tools they need to generate high-quality data and gain deeper insights into the biology of inhibitory neurotransmission.