Antibodies & immunoassays for small molecules ImmuSmol products trusted by scientists and highlighted in recent publications!
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Here below brief descriptions of recent features studies where some of our top products have been used and have helped advance research.
Guo et al., Journal of Pathology, 2022
In this work, the authors demonstrated the engagement of the Kynurenine pathway – through IDO2 – in heart, lung and brain from COVID-19 patients. In particular, they demonstrated through the use of ImmuSmol antibodies and immunohistochemistry, the accumulation of key metabolites including 3OH-Anthranilic Acid (# IS001) and Quinolinic Acid (# IS1010).
Honke et al., Plos Biology, 2022
Authors nicely presented the ability of B cells to produce catecholamines upon Toll Like Receptor 9 (TLR9) stimulation by CpG. Indeed, TLR9 activation was associated with an increased expression of Tyrosine Hydroxylase – an enzyme converting L-Tyrosine to L-DOPA – as well as Beta adrenergic receptors. These findings were supported through the use of our ELISA kits enabling detection of Dopamine and Noradrenaline (# BA-E-5500). Finally, the authors highlighted the suppressive function of catecholamines via an autocrine/paracrine mechanism.
Lischka et al., Nutrients, 2022
In this prospective study, the objective was to evaluate the impact of pediatric obesity on the Tryptophan catabolism through both the Kynurenine and Serotonin pathways. Tryptophan and Kynurenine levels were measured in plasma samples using ImmuSmol ELISA kits (# ISE-2227). A positive association between Body Mass Index (BMI) and IDO activity – as captured through the Kyn to Trp Ratio – was observed, an event that could underline metabolic disorders associated with pediatric obesity.
Browse more product citations below:
BA-E-1900 5-Hydroxyindoleacetic acid ELISA kit
- Nicotinic acetylcholine receptors expressed by striatal interneurons inhibit striatal activity and control striatal-dependent behaviors, The Journal of Neuroscience, 2022
- Increased serum diamine oxidase activity in nonallergic patients with migraine, European Journal of Clinical Investigation, 2022
- Apathy is not associated with a panel of biomarkers in older adults with HIV disease, Journal of Psychosomatic Research, 2022
BA-E-2200 Kynurenine ELISA kit, IS-I-0100 Quinolinic Acid ELISA kit and BA-E-2700 Tryptophan ELISA kit
- Alzheimer’s-like signaling in brains of COVID-19 patients, Alzheimer’s & Dementia, 2021
IS-I-0200 Kynurenic Acid ELISA kit
- Antidepressant- and anxiolytic-like activities of Rosmarinus officinalis extract in rodent models: Involvement of oxytocinergic system, Biomedicine & Pharmacotherapy, 2021
BA-E-6600 3 Catecholamines ELISA kit and BA-E-5900 Serotonin ELISA kit
- Cancer-associated fibroblasts educate normal fibroblaststo facilitate cancer cell spreading and T-cell suppression, Molecular Oncology, 2021
BA-E-2200 Kynurenine ELISA kit
- Ninjin’yoeito, a traditional Japanese medicine, increases dopamine content in PC12 cells, Bioscience, Biotechnology, and Biochemistry, 2021
- The Role of Indoleamine 2,3-Dioxygenase in Renal Tubular Epithelial Cells Senescence under Anoxia or Reoxygenation, Biomolecules, 2021
ISE-2227 Kynurenine/Tryptophan ELISA pack
- Plasma Kynurenine-to- Tryptophan Ratio, a Highly Sensitive Blood-Based Diagnostic Tool for Tuberculosis in Pregnant Women Living With Human Immunodeficiency Virus (HIV), Clinical Infectious Diseases, 2021
ISE-2227 Kynurenine/Tryptophan ELISA pack
- Astrocyte-derived TNF and glutamate critically modulate microglia activation by methamphetamine, Neuropsychopharmacology, 2021
IS-I-0100 Quinolinic Acid ELISA kit
- STING activation normalizes the intraperitoneal vascular-immune microenvironment and suppresses peritoneal carcinomatosis of colon cancer, Journal of Immunotherapy of Cancer
BA-E-2200 Kynurenine ELISA kit
- Role of indoleamine 2,3-dioxygenase in ischemia-reperfusion injury of renal tubular epithelial cells, Molecular Medicine Reports
ISE-2227 Kynurenine/Tryptophan ELISA pack
- The effects of high-monosaccharide diets on development and biochemical composition of white-eyed mutant strain of house cricket (Acheta domesticus), Scientific reports, 2021
ISE-2227 Kynurenine/Tryptophan ELISA pack and BA-E-5900 Serotonin ELISA kit
IS1005 Dopamine Ab and STAINperfect
BA-E-5300 Dopamine ELISA kit and BA-E-5900 Serotonin ELISA kit
- Alkyne-Tagged Dopamines as Versatile Analogue Probes for Dopaminergic System Analysis, Analytical Chemistry, 2021
IS1005 Dopamine Ab and STAINperfect
- Paliperidone Reversion of Maternal Immune Activation-Induced Changes on Brain Serotonin and Kynurenine Pathways, Front Pharmacol., 2021
ISE-2227 Kynurenine/Tryptophan ELISA pack
- Deep learning model enables the discovery of a novel immunotherapeutic agent regulating the kynurenine pathway, Oncoimmunology, 2021
BA-E-2200 Kynurenine ELISA kit and BA-E-2700 Tryptophan ELISA kit
- Quantification of normetanephrine in canine urine using ELISA: evaluation of factors affecting results, J Vet Diagn Invest, 2021
BA-E-8600 Metanephrnine-Normetanephrine ELISA kit
- Methoxphenidine (MXP) induced abnormalities: Addictive and schizophrenia-related behaviours based on imbalance of neurochemicals in the brain, British Journal of Pharmacology, 2021
- Circulating concentrations of citrulline, neopterin, kynurenine, and tryptophan during chemoradiation in patients with cervical carcinoma, Pteridines, 2021
BA-E-2200 Kynurenine ELISA kit and BA-E-2700 Tryptophan ELISA kit
- Early-life experiences altered the maturation of the lateral habenula in mouse models, resulting in behavioural disorders in adulthood, J Psychiatry Neuroscience, 2021
IS1006 GABA Ab and STAINperfect
- Mood Disorder in Systemic Lupus Erythematosus Induced by Antiribosomal P Protein Antibodies Associated with Decreased Serum and Brain Tryptophan, J Immunol., 2021
BA-E-2700 Tryptophan ELISA kit
- Abnormal Tryptophan Metabolism in HIV and Mycobacterium tuberculosis Infection, Front Microbiol., 2021