Homoarginine (hARG) ELISA kit out now!

HomoArginine (hArg) is a basic non-essential amino acid that exerts beneficial effects on vascular homeostasis, more likely through the increase of nitric oxide (NO) that can be explained through two mechanisms since hArg i) serves as a precursor of NO and ii) favors the elevation of L-Arg – main substrate of NO synthase – by inhibiting the enzyme Arginase. Our IS-I-0500 ELISA kit allows for the determination of hArg in serum and plasma samples in a minimal sample volume of 20μL and with a sensitivity of 125nM.

(A) Typical standard curve obtained with the hArg ELISA kit where the optical density is inversely correlated with hArg levels within a linear range of 0.32 – 12.5μM. (B) hArg was quantified in human serum samples from 40 healthy subjects using IS-I-0500 ELISA kit or by liquid chromatography–mass spectrometry (LC/MS). Correlation study showed R2=0.9642, thereby confirming the accuracy of the immunoassay.